2,603 research outputs found
Hexagons become second if symmetry is broken
Pattern formation on the free surface of a magnetic fluid subjected to a
magnetic field is investigated experimentally. By tilting the magnetic field
the symmetry can be broken in a controllable manner. When increasing the
amplitude of the tilted field, the flat surface gives way to liquid ridges. A
further increase results in a hysteretic transition to a pattern of stretched
hexagons. The instabilities are detected by means of a linear array of magnetic
hall sensors and compared with theoretical predictions.Comment: accepted for publication by Physical Review E/Rapid Communicatio
Walks of molecular motors in two and three dimensions
Molecular motors interacting with cytoskeletal filaments undergo peculiar
random walks consisting of alternating sequences of directed movements along
the filaments and diffusive motion in the surrounding solution. An ensemble of
motors is studied which interacts with a single filament in two and three
dimensions. The time evolution of the probability distribution for the bound
and unbound motors is determined analytically. The diffusion of the motors is
strongly enhanced parallel to the filament. The analytical expressions are in
excellent agreement with the results of Monte Carlo simulations.Comment: 7 pages, 2 figures, to be published in Europhys. Let
Equilibration of isolated macroscopic quantum systems
We investigate the equilibration of an isolated macroscopic quantum system in
the sense that deviations from a steady state become unmeasurably small for the
overwhelming majority of times within any sufficiently large time interval. The
main requirements are that the initial state, possibly far from equilibrium,
exhibits a macroscopic population of at most one energy level and that
degeneracies of energy eigenvalues and of energy gaps (differences of energy
eigenvalues) are not of exceedingly large multiplicities. Our approach closely
follows and extends recent works by Short and Farrelly [2012 New J. Phys. 14
013063], in particular going beyond the realm of finite-dimensional systems and
large effective dimensions.Comment: 19 page
Weak noise approach to the logistic map
Using a nonperturbative weak noise approach we investigate the interference
of noise and chaos in simple 1D maps. We replace the noise-driven 1D map by an
area-preserving 2D map modelling the Poincare sections of a conserved dynamical
system with unbounded energy manifolds. We analyze the properties of the 2D map
and draw conclusions concerning the interference of noise on the nonlinear time
evolution. We apply this technique to the standard period-doubling sequence in
the logistic map. From the 2D area-preserving analogue we, in addition to the
usual period-doubling sequence, obtain a series of period doubled cycles which
are elliptic in nature. These cycles are spinning off the real axis at
parameters values corresponding to the standard period doubling events.Comment: 22 pages in revtex and 8 figures in ep
Brownian motion exhibiting absolute negative mobility
We consider a single Brownian particle in a spatially symmetric, periodic
system far from thermal equilibrium. This setup can be readily realized
experimentally. Upon application of an external static force F, the average
particle velocity is negative for F>0 and positive for F<0 (absolute negative
mobility).Comment: 4 pages, 3 figures, to be published in PR
On the formation of Wigner molecules in small quantum dots
It was recently argued that in small quantum dots the electrons could
crystallize at much higher densities than in the infinite two-dimensional
electron gas. We compare predictions that the onset of spin polarization and
the formation of Wigner molecules occurs at a density parameter to the results of a straight-forward diagonalization of the Hamiltonian
matrix
Electrical activity-triggered glucagon-like peptide-1 secretion from primary murine L-cells
Glucagon like peptide 1 (GLP-1) based therapies are now widely used for the treatment of type 2 diabetes. Developing our understanding of intestinal GLP-1 release may facilitate the development of new therapeutics aimed at targeting the GLP-1 producing L-cells. This study was undertaken to characterise the electrical activity of primary L-cells and the importance of voltage gated sodium and calcium channels for GLP-1 secretion. Primary murine L-cells were identified and purified using transgenic mice expressing a fluorescent protein driven by the proglucagon promoter. Fluorescent L-cells were identified within primary colonic cultures for patch clamp recordings. GLP-1 secretion was measured from primary colonic cultures. L-cells purified by flow cytometry were used to measure gene expression by microarray and quantitative RT-PCR. Electrical activity in L-cells was due to large voltage gated sodium currents, inhibition of which by tetrodotoxin reduced both basal and glutamine-stimulated GLP-1 secretion. Voltage gated calcium channels were predominantly of the L-type, Q-type and T-type, by expression analysis, consistent with the finding that GLP-1 release was blocked both by nifedipine and Ï-conotoxin MVIIC. We observed large voltage-dependent potassium currents, but only a small chromanol sensitive current that might be attributable to KCNQ1. GLP-1 release from primary L-cells is linked to electrical activity and activation of L-type and Q-type calcium currents. The concept of an electrically excitable L-cell provides a basis for understanding how GLP-1 release may be modulated by nutrient, hormonal and pharmaceutical stimuli
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